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Jnana Therapeutics Closes $107M Series C Funding, Announces New Partnership with Big Pharma Roche

Jnana Therapeutics closed its $107 million series C round, adding Bain Capital Life Sciences to an investor team that already includes Pfizer and RA Capital Management.

The funding comes more than a year after the Boston-based biotech company raised $50 million for a series B.

The proceeds will be used to progress the company’s program in phenylketonuria, a rare genetic metabolic disease, through a clinical proof-of-concept study, and to advance additional wholly owned, potential first-in-class medicines in immune-mediated diseases and cancer.

Jnana also announced a collaboration with Swiss healthcare behemoth Roche. Jnana will receive an upfront payment of $50 million, significant near-term milestone payments, and additional potential future payments that could exceed $2 billion, as well as tiered royalties.

In exchange, Jnana is contributing discovery and preclinical work on “multiple” targets spanning cancer, immune-mediated diseases and neurology.

“Roche has been a valuable strategic partner and we are proud that our success to date has led to the opportunity to broaden our work together in immune-mediated and neurological diseases, as well as to extend our collaboration into cancer,” said Joanne Kotz, co-founder and CEO of Jnana Therapeutics.

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About Joe Palmisano

Joe Palmisano is editorial director of Connect Money, where he oversees daily coverage of alternative assets, direct investments, financial advisory and the economy. He brings three decades of experience as a financial journalist, analyst and portfolio manager. Before joining Connect Money, Palmisano wrote for The Wall Street Journal, covering foreign exchange, global fixed-income and equity markets. He later served as a senior research analyst and portfolio manager, producing market analysis and managing foreign exchange and U.S. equity portfolios for FX Concepts. His work has also appeared in SFO Magazine and CMT Association publications. Palmisano earned a bachelor’s degree in finance from The American University and holds the Chartered Market Technician (CMT) designation and is a member of the CFA Institute.