DJIA38904.04 307.06
S&P 5005204.34 57.13
NASDAQ16248.52 199.44
Russell 20002060.10 8.70
German DAX18163.94 -238.49
FTSE 1007911.16 -64.73
CAC 408061.31 -90.24
EuroStoxx 505013.35 -57.20
Nikkei 22538992.08 -781.06
Hang Seng16723.92 -1.18
Shanghai Comp3069.30 -5.66
KOSPI2714.21 -27.79
Bloomberg Comm IDX102.90 0.64
WTI Crude-fut91.17 0.01
Brent Crude-fut86.57 1.15
Natural Gas1.79 0.00
Gasoline-fut2.79 -0.01
Gold-fut2345.40 33.50
Silver-fut27.50 0.46
Platinum-fut940.60 -5.50
Palladium-fut1007.40 -23.60
Copper-fut423.60 1.85
Aluminum-spot1815.00 0.00
Coffee-fut212.50 5.75
Soybeans-fut1185.00 5.00
Wheat-fut567.25 11.00
Bitcoin67976.00 304.00
Ethereum USD3328.10 56.27
Litecoin98.71 0.69
Dogecoin0.18 0.00
EUR/USD1.0862 0.0007
USD/JPY151.72 -0.02
GBP/USD1.2678 0.0016
USD/CHF0.9044 -0.0014
USD IDX104.28 0.08
US 10-Yr TR4.4 0.091
GER 10-Yr TR2.406 0.007
UK 10-Yr TR4.064 -0.005
JAP 10-Yr TR0.771 -0.004
Fed Funds5.5 0
SOFR5.32 0

Sub Markets

Topics

Direct Investment  + M&As  | 
Aeglea BioTherapeutics Buys Spyre, Shares Rocket Over 400%

Aeglea BioTherapeutics Buys Spyre, Shares Rocket Over 400%

Aeglea BioTherapeutics, which has been exploring strategic alternatives given its poor stock performance, is merging with biotech firm Spyre Therapeutics in a deal that coincides with a private placement.

The merger is a stock-for-stock deal with Austin, TX-based Aeglea buying Spyre’s existing equity interest in exchange for roughly 13 million common Aeglea shares and 365,000 shares of series A preferred stock.

The private investment in public equity, or PIPE will give the combined company $210 million in funding before expenses. At the close, the company is expected to have about $220 million in cash and cash equivalents to fund its operations into 2026.

Waltham, MA-based Spyre is the second spinout of Paragon Therapeutics. The firm develops antibody drugs for inflammatory bowel disease, or IBD. The acquisition adds Spyre’s two parallel lead programs featuring the antibodies SPY001 and SPY002 targeting a4b7 and TL1A, respectively, to Aeglea’s portfolio.

“The company is making rapid progress advancing their two parallel lead programs into the clinic, and we believe these programs will enable us to capture a sizable share of the growing IBD market,” said Jonathan D. Alspaugh, President and CFO, Aeglea.

Aeglea stock was trading at just $0.12 per share ahead of the announcement. The price has since jumped over 400% to $0.55, although this remains below Nasdaq’s $1 threshold to remain listed.

Connect

Inside The Story

Aeglea BioTherapeutics Spyre Therapeutics

About Joe Palmisano

Joe Palmisano is Editorial Director for Connect Money, where he brings nearly three decades experience of market insights as a financial journalist, analyst and senior portfolio manager for leading financial publications, advisory firms, and hedge funds. In his role as Editorial Director, Joe is responsible for the selection of content and creation of daily business news covering the financial markets, including Alternative Assets, Direct Investment and Financial Advisory services. Before joining Connect Money, Joe was a financial journalist for the Wall Street Journal, regularly publishing feature stories and trend pieces on the foreign exchange, global fixed income and equity markets. Joe parlayed his experience as a financial journalist into roles as a Senior Research Analyst and Portfolio Manager, writing daily and weekly market analysis and managing a FX and US equity portfolio. Joe was also a contributing writer for industry magazines and publications, including SFO Magazine and the CMT Association. Joe earned a B.S.B.A. in Finance from The American University. He holds the Chartered Market Technician (CMT) designation and is a member of the CFA Institute.

New call-to-action