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Alternative Assets  + Real Estate  | 
Breakthrough Properties Raises $430M in First Close for Life Sciences Fund 

Breakthrough Properties Raises $430M in First Close for Life Sciences Fund 

Breakthrough Properties—a joint venture between Tishman Speyer and Bellco Capital—has completed the first closing of its Breakthrough Properties Growth Portfolio II fund, securing $430 million in capital and co-investment commitments. The fund will invest in a diversified portfolio of Class A life science assets across leading U.S. and European markets. 

The new fund follows Breakthrough’s $3 billion inaugural life science vehicle, closed in 2022, which supported a nearly six-million-square-foot portfolio spanning purpose-built developments, value-add conversions, and core/core+ properties in eight of the world’s most active R&D hubs. More than 60% of Breakthrough’s global portfolio is leased to investment-grade life science leaders such as Pfizer, AstraZeneca, Eli Lilly, Bristol Myers Squibb, BD and Roche. 

Breakthrough’s flagship developments include Torrey Heights in San Diego, One Helix in Amsterdam and One Milestone at Harvard’s forthcoming Enterprise Research Campus in Boston. 

Participants in the first closing included global asset managers, investment advisors, pension funds and family offices. Additional closings are planned for 2026. 

“Transitory market dynamics have generated the opportunity to acquire high-quality assets at heavily disrupted pricing and to capitalize on the sector’s long-term structural tailwinds,” said Dan Belldegrun, CEO of Breakthrough Properties. “The incredible power of science is only accelerating, generalist investors are retreating and new supply is entirely shut off. We believe these are precisely the ingredients for a fantastic investment vintage.” 

Pictured: Torrey Heights by Breakthrough – Photos by Jason O’Rear 

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About Joe Palmisano

Joe Palmisano is editorial director of Connect Money, where he oversees daily coverage of alternative assets, direct investments, financial advisory and the economy. He brings three decades of experience as a financial journalist, analyst and portfolio manager. Before joining Connect Money, Palmisano wrote for The Wall Street Journal, covering foreign exchange, global fixed-income and equity markets. He later served as a senior research analyst and portfolio manager, producing market analysis and managing foreign exchange and U.S. equity portfolios for FX Concepts. His work has also appeared in SFO Magazine and CMT Association publications. Palmisano earned a bachelor’s degree in finance from The American University and holds the Chartered Market Technician (CMT) designation and is a member of the CFA Institute.